British Journal of Anaesthesia Leeds Dosage of Ici 35 868
نویسندگان
چکیده
McCubbin, T. D., Brown, J. H., Dewar, K. M. S., Jones, C. J., and Spence, A. A. (1979). Glycopyrrolate as a premedicant: comparison with atropine. Br. J. Anaesth., 51, 885. Rupreht, J. (1980). Physostigmine rcversaj of diazepam. Anesthesiology, (in press). Dworacek, B. (1976). Central anticholinergic syndrome in anaesthetic practice. Acta Anaesthesiol. Belg., 27, 45. Selenati, A. (1979). Recettori cerebrali e neuromediatori. Acquisizioni recenti e applicazioni cliniche. Thesis, University of Pavia, No. 14 05 69.
منابع مشابه
Comparison of the respiratory effects of ICI 35 868 and thiopentone in the rabbit.
The effects of thiopentone and ICI 35 868 on minute volume, respiratory frequency, tidal volume and arterialized venous PCO2, pH and standard bicarbonate have been compared in the rabbit. ICI 35 868 has two to three times the potency of thiopentone, but equivalent anaesthetic doses cause similar decreases in minute volume. ICI 35 868 decreased tidal volume to a greater extent than thiopentone. ...
متن کاملAnimal studies of the anaesthetic activity of ICI 35 868.
The activity of a new i.v. anesthetic agent ICI 35 868, a compound unrelated to currently used barbiturate, eugenol or steroid agents, has been examined in a range of animal species. Some of the properties of ICI 35 868 resemble those of thiopentone in that it is a rapidly acting agent which produces anaesthesia of short duration and without excitatory side-effects. Both agents have a similar t...
متن کاملPharmacokinetics in laboratory animals of ICI 35 868, a new i.v. anaesthetic agent.
Blood concentrations of ICI 35 868 have been determined in rat, pig, rabbit and cat after single i.v. injections. In all species the initial distribution volume was greater than blood volume and the overall distribution volume was large. Half-lives of the distribution phase were extremely short (1-6 min) and the terminal half-lives were also short (16-55 min). In all species examined a correlat...
متن کاملA study of three doses of ici 35 868 for induction and maintenance of anaesthesia.
Three doses (1.5, 2.0 and 2.5 mg kg-1) of diisopropyl phenol (ICI 35 868) were compared for induction and maintenance of anaesthesia in healthy females undergoing short gynaecological procedures. Induction of anaesthesia was smooth and rapid. Cardiovascular changes (which were dose-dependent) included a decrease in arterial pressure and an increase in heart rate. These changes were magnitudes c...
متن کاملHaemodynamic effects of infusions of diisopropyl phenol (ICI 35 868) during nitrous oxide anaesthesia in man.
The haemodynamic effects of diisopropyl phenol in cremophor EL at infusion rates of 50-55 and 100 micrograms kg-1 min-1 in combination with inhalation of 67% nitrous oxide have been studied during spontaneous and controlled ventilation in patients premedicated with morphine and atropine. Under all the conditions studied diisopropyl phenol supplementation of nitrous oxide anaesthesia was associa...
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